Some info taken from rootsweb from Tex Dick. Full link is : http://archiver.rootsweb.ancestry.com/th/read/REDWINE/2002-02/1013772745 

Below is part of an email From: "Barbara Hill" < bhill@uclink4.berkeley.edu>

Many of the stories I've uploaded are from his large page of research. 

Nelson's book clearly shows that Jacob's father was named (originally)
Ludwig RIETHWEIL (or "READWILE") and that the name evolved (or devolved?)
into "Lewis Redwile" and then "Redwine." (Ludwig in German is Lewis/Louis
in English.) Her book includes photocopies of Bible pages showing the
evolution of the surname, and a copy of Ludwig/Lewis's will naming his son
Jacob among others.

Ludwig was indeed married to a woman named Barbara, last name
unknown. Maybe it was STONER as per legend, or maybe it was STEINER which
would have been probably the German equivalent and more likely. But it is
not known whether this Barbara was the mother of all of Ludwig's children
(five known).

The surname RIETHWEIL in turn seems to have been shortened from
"RIETHWEILER" in Germany. This surname means "someone who comes from
Riethweil." There just happens to be such a place - Riethweil - in
Switzerland. You can find it on a good map. "Rieth" is German for "reed"
and "weil" is a peculiarly Swiss-German dialect form of the old Latin word
"villa" meaning a village or town. I once mentioned the place name
Riethweil to a Swiss citizen, and he said he had been there, and that it is
located in a swampy or marshy area (thus "reed village"). This origin of
the surname would seem to match the origins of the Palatinate Germans, who
were largely of Swiss origin and who moved into the upper Rhine Valley of
Germany after its population had been decimated by war (if I recall
correctly). Martha Redwine Nelson's book has lots more information but it
was published in 1990 and may be out of print and I don't know if she is
still around. Most of it follows her own line, but the first 50 pages are
of interest to all Redwine descendants.